Premarin

Description

General information about Premarin in USA

Premarin is a blend of estrogen hormones used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Other uses include preventing osteoporosis in postmenopausal women and replacing estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. Premarin is sometimes used in the treatment of cancer in women and men.

Estrogen is a female sex hormone produced by the ovaries. Estrogen is needed for many processes in the body. Premarin should not be used to prevent heart disease or dementia because this drug may increase your risk of developing these conditions. Premarin may also be used for other purposes not listed in this medication guide.

Precautions in USA

Do not use this medication if you have any of the following conditions: history of heart attack, stroke, or blood clot (especially in the lungs or lower body), liver disease, abnormal vaginal bleeding or hormonal cancer such as breast or uterine cancer. This medicine can cause birth defects in an unborn baby. Do not use Premarin if you are pregnant.

Long-term treatment with Premarin may increase your risk of breast cancer, heart attack, or stroke. Speak with your doctor about your individual risks before using Premarin long term, especially if you smoke or are overweight.Your doctor should check your progress regularly (every 3 to 6 months) to determine if you should continue this treatment.

Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using Premarin. Premarin should not be used to prevent heart disease or dementia because this drug may increase your risk of developing these conditions.

Side effects

• Bleeding and spotting
• Breast pain, tenderness or enlargement
• Headache / Migraine
• Bowel problems, such as nausea, abdominal pain, bloating, flatulence, indigestion • Leg cramps
• Fatigue
• Weight changes
• Vaginal thrush
• Depression
• Anxiety
• Dizziness
• Changes in libido
• Increase in blood pressure
• Gallbladder disease
• Swelling of the ankles due to fluid retention (peripheral edema)
• Skin reactions such as rash and itching
• Penetration of the corneal curvature which can make contact lenses uncomfortable.
• Premenstrual-like symptoms
• Disturbance of liver function
• Uneven brown patches on the skin, usually on the face (chloasma)
• Blood clots in the blood